FFA/Triglyceride Cycle
FFA_Cycle.jpg
Figure 1. The triglyceride/fatty acid cycle in mammals. Reshef, L, et al. 2003. Journal Bio. Chem. 278, 30413-30416.

The FFA/Triglyceride cycle recycles fatty acids. Studies in human adults, new born infants and animals show that only a small fractions of the FFA released as a result of lipolysis in white adipose tissues are oxidized. A majority of the fatty acids are re-esterified to triglycerides in various tissues. The FFA cycling varies in different studies in humans.[1] The 75% of free fatty acids released during lipolysis is recycled. The reasons why it is fixed at 75% is yet to be determined. The free fatty acid converted back into triglycerides can be used to generate glycerol through a process called glyceroneogensis in white adipose tissues (WAT) and in brown adipose tissue (BAT). The free fatty acid (FFA) that is not converted back into triglycerides are used in fat oxidation.[1]

Pathway 1
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  1. ^ Reshef, L, et al. (2003). Journal of Biological Chemistry. 278, 30413-30416